2-Nitroaniline
- o-Nitroaniline
- 1-Amino-2-nitrobenzene
2-Nitroaniline | |
| |
| Formula | C6H6N2O2 |
| Structure | |
| Description | Orange solid with a musty odor. |
| Uses | Chemical intermediate for ci pigment yellow 5, orange 2, yellow 7, vat red 15, vat orange 7, ci pigment orange 43, vat red 14, disperse yellow 10. |
| Registry Numbers and Inventories. | |
| CAS | 88-74-4 |
| EC (EINECS/ELINCS) | 201-855-4 |
| EC Index Number | 612-012-00-9 |
| EC Class | Toxic; Danger of cumulative effects; Dangerous for the Environment |
| EC Risk Phrase | R 23/24/25 33 52/53 |
| EC Safety Phrase | S 28 36/37 45 61 |
| RTECS | BY6650000 |
| RTECS class | Mutagen |
| UN (DOT) | 1661 |
| Merck | 12,6680 |
| Beilstein/Gmelin | 509275 |
| Beilstein Reference | 4-12-00-01563 |
| RCRA | K101 |
| Canada DSL/NDSL | DSL |
| US TSCA | Listed |
| Austrailia AICS | Listed |
| New Zealand | Listed |
| Japan ENCS (MITI) | Listed |
| Korea ECL | Listed |
| Properties. | |
| Formula | C6H6N2O2 |
| Formula mass | 138.13 |
| Melting point, °C | 68 - 71 |
| Boiling point, °C | 284 |
| Vapor pressure, mmHg | 0.003 (25 C) |
| Density | 1.446 g/cm3 (20 C) |
| Solubility in water | 1.1 g/L |
| Surface tension | 40.4 g/s2 (131 C) |
| Refractive index | 1.5362 (100 C) |
| Partition coefficient, pKow | 1.83 |
| Heat of fusion | 16.1 kJ/mol |
| Heat of vaporization | 52.4 kJ/mol |
| Heat of combustion | -3029 kJ/mol |
| Hazards and Protection. | |
| Storage | Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked. Keep containers tightly closed. |
| Handling | Wash thoroughly after handling. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. |
| Protection | Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. |
| Respirators | Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. |
| Small spills/leaks | Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation. |
| Disposal code | 9 |
| Stability | Stable under normal temperatures and pressures. |
| Incompatibilities | Acids - acid chlorides - acid anhydrides - chloroformates - strong oxidizing agents. |
| Decomposition | Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen. |
| Fire. | ||||
| Flash Point,°C | 126 | |||
| Autoignition, °C | 521 | |||
| Upper exp. limit, % | 9.8 | |||
| Lower exp. limit, % | 1.5 | |||
| Fire fighting | Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. May polymerize explosively when involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Combustible material; may burn but does not ignite readily. Extinguishing media: Cool containers with flooding quantities of water until well after fire is out. In case of fire, use water spray, dry chemical, carbon dioxide, or alcohol-resistant foam. | |||
| Fire potential | Slightly flammable. Flammable at elevated temperatures - moderate hazard. | |||
| Hazards | When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. | |||
| Combustion products | Toxic oxides of nitrogen may form in fire. | |||
| NFPA | Health | 1 | ||
| Reactivity | 0 | |||
| Health. | |
| Exposure limit(s) | NIOSH: Potential Occupational Carcinogen. |
| Exposure effects | Acute poisoning may cause rapid heart rate and rapid breathing. Severe headache, CNS disturbances, and tremor may occur. A high incidence of gynecological disorders and excess frequency of spontaneous abortions have been noted. The fetal liver can n-oxygenate aniline to form phenylhydroxylamine. Fetal effects include higher levels of methemoglobin those found in than the mother. Fetal poisoning may occur. <br>No data were available to assess the potential effects of exposure to aniline during lactation. <br>No information about possible male reproductive effects was found in available references at the time of this review |
| Ingestion | May be harmful if swallowed. Causes digestive tract irritation. |
| Inhalation | Dust is irritating to the respiratory tract. |
| Skin | Causes skin irritation. |
| Eyes | Dust may cause mechanical irritation. |
First aid | |
| Ingestion | If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. |
| Inhalation | Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. |
| Skin | Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. |
| Eyes | Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. |
| Transport. | ||
| UN number | 1661 |  |
| Response guide | 153 | |
| Hazard class | 6.1 | |
| Packing Group | II | |
| USCG CHRIS Code | NTA | |
| HS Code | 2921 42 10 | |