Carbofuran

  • 2,3-Dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamate
  • 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate
  • 2,2-Dimethyl-2,3-dihydro-7-Benzofuranyl-n-methylcarbamate
Formula C12H15NO3
Structure
Description Carbofuran is a white, odorless solid dissolved in a liquid carrier.
Uses Broad spectrum insecticide, nematocide.

Registry Numbers and Inventories.
CAS 1563-66-2
EC (EINECS/ELINCS) 216-353-0
EC Index Number 006-026-00-9
EC Class Very toxic; Dangerous for the Environment
RTECS FB9450000
RTECS class Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector; Human Data
UN (DOT) 2757
Merck 12,1851
Beilstein/Gmelin 1428746
Beilstein Reference 5-17-04-00048
RCRA P127
EPA OPP 90601
Swiss Giftliste 1 G-5400
Canada DSL/NDSL NDSL
US TSCA Listed
Austrailia AICS Listed
New Zealand Listed
Japan ENCS (MITI) Listed
Korea ECL Listed

Odor Threshold Odor threshold Odorless
Properties.
Formula C12H15NO3
Formula mass 221.26
Boiling point, C 313
Vapor pressure, mmHg 0.0005 (25 C)
Vapor density (air=1) 1.18
Density 1.18 g/cm3 (20 C)
Solubility in water 0.07 g / 100 ml
pKa/pKb 11.90 pKa)
Partition coefficient, pKow 2.32
Heat of vaporization 55.4 kJ/mol

Hazards and Protection.
Storage Tightly closed containers. Keep away from heat and water.
Handling All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection Wear appropriate chemical protective clothing.
Respirators Wear positive pressure self-contained breathing apparatus.
Small spills/leaks Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors. Land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water. Water spill: Use natural deep water pockets, excavated lagoons, or sand bag barriers to trap material at bottom. If dissolved, in region of 10 ppm or greater concentration, apply activated carbon at ten times the spilled amount. Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.
Stability Stable under neutral or acid conditions, unstable in alkaline media.
Incompatibilities Incompatible with strong acids and bases, and especially

Fire.
Flash Point,C 143
Fire fighting Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Solid streams of water may be ineffective. Use foam, dry chemical, or carbon dioxide.
Fire potential Non-Combustible
Hazards May release nitrogen oxides. Containers may explode in heat of fire. Avoid alkalies. Stable under neutral or acid conditions.
Combustion products Very toxic dust and irritating fumes produced at fire temperatures.

Health.
Exposure limit(s) TLV: ppm; 0.1 mg/m3 (ACGIH 1993-1993). NIOSH REL: TWA 0.1 mg/m3
Poison_Class 2
Exposure effects Hypoventilation and rapid heart rate or low heart rate may occur. Headache, blurred vision, tremor, seizures, paresis, mental depression, coma, delayed neuropathies, various dystonias, weakness, and muscle twitching may be noted. Teratogenic lesions, and adverse effects during pregnancy may occur. <br>Carbofuran did not appear in the milk of cows fed the pesticide for an extended period of time. <br>Carbofuran has been shown to cross the placental barrier in a human overdose case. <br>No information about possible male reproductive effects was found in available references.
   Ingestion Nausea, vomiting, diarrhea, and abdominal cramping may be noted.
   Inhalation Copious secretions, respiratory insufficiency, and pulmonary edema may develop in serious poisonings.
   Skin Diaphoresis may be noted. Cyanosis may occur following severe respiratory depression.
   Eyes Blurred vision, constriction of the pupil, and eye irritation may commonly occur. Mydriasis may occur.

First aid
 
   Ingestion Do not induce emesis. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
   Skin Remove contaminated clothing and jewelry. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing.
   Eyes Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number 2757
Response guide 151
Hazard class 6.1
Packing Group I; II; III  
USCG CHRIS Code CBF  
Std. Transport # 4921524