Dichloroethyl ether

  • Di(2-chloroethyl ether
  • 1,1'-Oxybis[2-chloroethane]
  • bis(2-Chlorethyl)ether
  • sym-Dichloroethyl ether
Formula(ClCH2CH2)2O
Structure
DescriptionColorless liquid with a chlorinated solvent-like odor.
UsesReagent for organic synthesis, solvent.

Registry Numbers and Inventories.
CAS111-44-4
EC (EINECS/ELINCS)203-870-1
EC Index Number603-029-00-2
EC ClassFlammable; Very toxic; Harmful
EC Risk PhraseR 10 26/27/28 68
EC Safety PhraseS 7/9 27 38 45
RTECSKN0875000
RTECS class Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Primary Irritant
UN (DOT)1916
Merck13,3091
Beilstein/Gmelin605317
Beilstein Reference4-01-00-01375
RCRAU025
EPA OPP 29501
Swiss Giftliste 1G-1520
Canada DSL/NDSLNDSL
US TSCAListed
Austrailia AICSListed
New ZealandListed
Japan ENCS (MITI) Listed

Odor Threshold Odor threshold 90 mg/m3
Properties.
Formula C4H8Cl2O
Formula mass 143.01
Melting point, C -44
Boiling point, C 178
Vapor pressure, mmHg 2 (30 C)
Vapor density (air=1) 4.93
Saturation Concentration 921 ppm (0.09%) at 20 C (calculated)
Critical temperature 429
Critical pressure 32.2
Density 1.22917 g/cm3 (12 C)
Solubility in water 10 g/L
Viscosity 2.37 cp (20 C)
Surface tension 37.9 g/s2 @ 19 C
Refractive index 1.4548 (20 C)
Dipole moment 2.47 D
Dielectric constant 20.5 (20 C)
Partition coefficient, pKow 1.29
Heat of fusion 8.7 kJ/mol
Heat of vaporization 38.38 kJ/mol
Heat of combustion -17470 kJ/mol

Hazards and Protection.
Storage Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area.
WHMIS B3 D1A D2B
Handling Wash thoroughly after handling. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Remove all sources of ignition. Use a spark-proof tool. A vapor suppressing foam may be used to reduce vapors.
Disposal code 9
Stability Stable under normal temperatures and pressures.
Incompatibilities Strong oxidizing agents, coatings, plastics, rubber.
Decomposition Hydrogen chloride, carbon monoxide, carbon dioxide.

Fire.
Flash Point,C55
Autoignition, C365
Lower exp. limit, %2.7
Fire fightingWear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.
Fire potentialModerately flammable. Combustion with moderate heating.
HazardsMay form phosgene or hydrogen chloride in fires. There is danger of explosion when ethers are heated or exposed to flames or sparks. Ethers tend to form peroxides; when ethers containing peroxides are heated, they can detonate. May be ignited by heat, sparks, or flames. Container may explode in heat of fire. Vapor explosion and poison hazard indoors, outdoors or in sewers. Decomposes in the presence of moisture to form hydrochloric acid. Emits toxic fumes when heated to decomposition. Reacts vigorously with oleum and chlorosulfonic acid. Ethers tend to form peroxides upon standing. Heating peroxide-containing ethers can cause detonation.
Combustion productsMay form phosgene or hydrogen chloride in fires.
NFPAHealth2
 Flammability2 
 Reactivity1 

Health.
Exposure limit(s)NIOSH REL: Ca TWA 5 ppm (30 mg/m3) ST 10 ppm (60 mg/m3) [skin] See Appendix A OSHA PEL: TWA 15 ppm (90 mg/m3) [skin] IDLH Ca [100 ppm]
CarcinoginCP65
Poison_Class2
Exposure effects Potential cancer hazard.
   IngestionHarmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts may cause CNS depression.
   InhalationMay be fatal if inhaled. Causes respiratory tract irritation. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. May cause burning sensation in the chest.
   SkinCauses skin irritation. May be fatal if absorbed through the skin. May cause irritation and dermatitis. May cause cyanosis of the extremities.
   Eyes Causes severe eye irritation. Lachrymator. May cause chemical conjunctivitis and corneal damage.

First aid
 
   IngestionIf victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   InhalationGet medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   EyesImmediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number1916
Response guide152
Hazard class 6.1
Packing GroupII  
USCG CHRIS CodeDEE  
USCG Compatatibility Group 41 Ethers
HS Code 2909 19 00 
Std. Transport # 4921550  
IMO Chemical Code 17
IMO Pollution Category B
IMO Hazard code S/P