Isophorone diisocyanate

  • 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate
  • 1,1,5,5-Tetramethylcyclohexane-a-1,3-diisocyanate
  • 5-Isocyanato-1-isocyanatomethyl-1,3,3-trimethylcoclohexane
FormulaC12H18N2O2
Structure
DescriptionColorless to slightly yellow liquid with a pungent odor.
UsesYields polyurethanes with high stability, resistance to light discoloration, and chemical resistance.

Registry Numbers and Inventories.
CAS4098-71-9
EC (EINECS/ELINCS)223-861-6
EC Index Number615-008-00-5
EC ClassToxic; Irritant; Sensitising; Dangerous for the Environment
EC Risk PhraseR 23 36/37/38 42/43 51/53
EC Safety PhraseS 26 28 38 45 61
RTECSNQ9370000
RTECS class Reproductive Effector
UN (DOT)2290
Beilstein/Gmelin2726467
Beilstein Reference6-13
Swiss Giftliste 1G-6847
Canada DSL/NDSLDSL
US TSCAListed
Austrailia AICSListed
New ZealandListed
Japan ENCS (MITI) Listed
Korea ECLListed

Properties.
Formula C12H18N2O2
Formula mass 222.29
Melting point, °C -60
Boiling point, °C 158
Vapor pressure, mmHg 0.0003
Saturation Concentration 0.40-0.53 ppm at 20 C (calculated)
Evaporization number Probably very low
Density 1.049 g/cm3 (20 C)
Solubility in water Reacts
Refractive index 1.482 (25 C)

Hazards and Protection.
Storage Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
WHMIS D1A D2A D2B
Handling All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection Wear appropriate protective gloves, clothing and goggles.
Respirators Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Do not use water.
Disposal code 9
Stability No data.
Incompatibilities Reacts with all substances containing active hydrogen atoms such as water, alcohols, phenols, amines, mercaptans, amides, urethanes and ureas.

Fire.
Flash Point,°C155
Autoignition, °C430
Upper exp. limit, %4.5
Lower exp. limit, %0.7
Fire fightingKeep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Wear positive pressure breathing apparatus and special protective clothing. Remove and isolate contaminated clothing at the site.Small fires: dry chemical, carbon dioxide, water spray or foam. Large fires: water spray, fog or foam. Move container from fire area if you can do so without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material.
Fire potentialCombustible material: may burn but does not ignite readily.
HazardsWhen heated to decomposition, it emits toxic fumes of nitrogen oxides.
Combustion productsFire will produce irritating, corrosive and/or toxic gases.
NFPAHealth2
 Flammability1 
 Reactivity1 
 SpecialW

Health.
Exposure limit(s)TLV: 0.005 ppm; 0.045 mg/m3 (skin) (ACGIH 1991-1992). NIOSH REL: TWA 0.005 ppm (0.045 mg/m3) ST 0.02 ppm (0.180 mg/m3) skin
Poison_Class2
Exposure effects No data were available to assess the teratogenic potential of this agent. <br>No data were available to assess the potential effects of exposure to this agent during pregnancy or lactation.
   IngestionGastrointestinal tract irritation could potentially occur.
   InhalationRespiratory tract irritation may occur. Pulmonary sensitization with bronchospasm on re-exposure is possible. Released oxides of nitrogen could produce severe irritation or pulmonary edema.
   SkinDirect contact produces skin irritation. Dermal hypersensitivity reactions may be seen on re-exposure.
   Eyes Irritation may result from direct eye contact. Exposure to vapors may produce irritation to the mucosa of the nose and throat.

First aid
 
   IngestionDo not induce vomiting - consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Observe patients with ingestion carefully for the possible development of esophageal or gastrointestinal tract irritation or burns. If signs or symptoms of esophageal irritation or burns are present, consider endoscopy to determine the extent of injury.
   InhalationMove patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Systemic antihistamine or corticosteroid therapy may be required for hypersensitivity reactions.
   EyesIrrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. As severe ocular injury may occur with direct eye contact, consider early ophthalmologic consultation.

Transport.
UN number2290
Response guide156
Hazard class 6.1
Packing GroupIII  
USCG CHRIS CodeIPD  
USCG Compatatibility Group 12 Isocyanates
HS Code 2929 10 90 
Std. Transport # 4925107  
IMO Chemical Code 17
IMO Pollution Category B
IMO Hazard code S/P