o-Phenylenediamine
- 1,2-Diaminobenzene
o-Phenylenediamine | |
| |
| Formula | 1,2-(NH2)2C6H4 |
| Structure | |
| Description | Colorless monoclinic crystals, darkens in air. |
| Uses | Manufacture of dyes, photographic developing agent, organic synthesis, laboratory reagent. |
| Registry Numbers and Inventories. | |
| CAS | 95-54-5 |
| EC (EINECS/ELINCS) | 202-430-6 |
| EC Index Number | 612-145-00-2 |
| EC Class | Carcinogenic Category 3; Mutagenic Category 3; Toxic; Harmful; Irritant; Sensitising; Dangerous for the Environment |
| EC Risk Phrase | R 20/21 25 36 40 43 50/53 68 |
| EC Safety Phrase | S 28 36/37 45 60 61 |
| RTECS | SS7875000 |
| RTECS class | Mutagen |
| UN (DOT) | 1673 |
| Merck | 12,7438 |
| Beilstein/Gmelin | 606074 |
| Beilstein Reference | 4-13-00-00038 |
| Swiss Giftliste 1 | G-8579 |
| Canada DSL/NDSL | DSL |
| US TSCA | Listed |
| Austrailia AICS | Listed |
| New Zealand | Listed |
| Japan ENCS (MITI) | Listed |
| Korea ECL | Listed |
| Properties. | |
| Formula | C6H8N2 |
| Formula mass | 108.14 |
| Melting point, °C | 103 |
| Boiling point, °C | 257 |
| Vapor pressure, mmHg | 0.015 (25 C) |
| Density | 1.21 g/cm3 |
| Solubility in water | 54 g/L |
| pKa/pKb | 9.54 (pKb) |
| Partition coefficient, pKow | 0.15 |
| Heat of fusion | 18.6 kJ/mol |
| Heat of vaporization | 45.5 kJ/mol |
| Heat of combustion | -3511 kJ/mol |
| Hazards and Protection. | |
| Storage | Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. |
| Handling | Wash thoroughly after handling. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse. |
| Protection | Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear a chemical apron. Wear appropriate clothing to prevent skin exposure. |
| Respirators | Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. |
| Small spills/leaks | Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. |
| Disposal code | 9 |
| Stability | Stable under normal temperatures and pressures. |
| Incompatibilities | Strong oxidizing agents. |
| Decomposition | Nitrogen oxides, carbon monoxide, carbon dioxide. |
| Fire. | ||||
| Flash Point,°C | 110 | |||
| Autoignition, °C | 540 | |||
| Upper exp. limit, % | 9.8 | |||
| Lower exp. limit, % | 1.5 | |||
| Fire fighting | Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode when heated. Combustible material; may burn but does not ignite readily. Extinguishing media: For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out. | |||
| Fire potential | This material is probably combustible. | |||
| Hazards | When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. | |||
| Combustion products | Fire may produce irritating, corrosive and/or toxic gases. | |||
| NFPA | Health | 3 | ||
| Flammability | 1 | |||
| Reactivity | 0 | |||
| Health. | |
| Exposure limit(s) | 0.1 mg/m3 TLV |
| Carcinogin | G-A3, CP65 |
| Poison_Class | 3 |
| Exposure effects | Prolonged or repeated skin contact may cause dermatitis. May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis, rapid heart rate, unconsciousness and possible death. |
| Ingestion | May cause irritation of the digestive tract. May cause liver and kidney damage. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. May be harmful if swallowed. Overexposure may cause methemoglobinemia. |
| Inhalation | Dust is irritating to the respiratory tract. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown blood. Inhalation of aniline causes anoxia due to the formation of methemoglobinemia. |
| Skin | May cause skin irritation. May be absorbed through the skin in harmful amounts. |
| Eyes | May cause eye irritation. May result in corneal injury. |
First aid | |
| Ingestion | Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Wash mouth out with water. |
| Inhalation | Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. DO NOT use mouth-to-mouth respiration. |
| Skin | Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse. |
| Eyes | Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. |
| Transport. | ||
| UN number | 1673 |  |
| Response guide | 153 | |
| Hazard class | 6.1 | |
| Packing Group | III | |
| USCG Compatatibility Group | 9. Aromatic amines | |
| HS Code | 2921 51 19 | |