2-Hexanone

  • Methyl n-butyl ketone
  • Propylacetone
  • n-Butyl methyl ketone
  • Hexan-2-one
Formula CH3COC4H9
Structure
Description A clear colorless liquid.
Uses Solvent for lacquers, ink thinners, nitrocellulose, resins, oils, fats and waxes.

Registry Numbers and Inventories.
CAS 591-78-6
EC (EINECS/ELINCS) 209-731-1
EC Index Number 606-030-00-6
EC Class Flammable; Toxic for reproduction Category 3; Toxic; Vapours may cause drowsiness and dizziness
EC Risk Phrase R 10 48/23 62 67
EC Safety Phrase S 36/37 45
RTECS MP1400000
RTECS class Mutagen; Reproductive Effector; Human Data; Primary Irritant
UN (DOT) 1224
Merck 12,6112
Beilstein/Gmelin 1737676
Beilstein Reference 4-01-00-03298
Swiss Giftliste 1 G-2440
Canada DSL/NDSL DSL
US TSCA Listed
Austrailia AICS Listed
New Zealand Listed
Japan ENCS (MITI) Listed
Korea ECL Listed

Odor Threshold Odor threshold 3 ppm
Properties.
Formula C6H12O
Formula mass 100.16
Melting point, °C -56.9
Boiling point, °C 127
Vapor pressure, mmHg 12
Vapor density (air=1) 3.45
Evaporization number 1.2 (butyl acetate=1)
Critical temperature 314
Critical pressure 32.44
Density 0.812 g/cm3 (20 C)
Solubility in water 14 g/L
Viscosity 0.58 cp (25 C)
Surface tension 25.49 g/s2
Refractive index 1.40061 (15 C)
Partition coefficient, pKow 1.38
Heat of fusion 7.5 kJ/mol
Heat of vaporization 43.03 kJ/mol
Heat of combustion -3686 kJ/mol

Hazards and Protection.
Storage Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container. Flammables-area.
Handling Wash thoroughly after handling. Use only in a well ventilated area. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Remove all sources of ignition.
Stability Stable under normal temperatures and pressures.
Incompatibilities Oxidizing agents, reducing agents, strong bases.
Decomposition Carbon monoxide, carbon dioxide.

Fire.
Flash Point,°C 25
Autoignition, °C 424
Upper exp. limit, % 8
Lower exp. limit, % 1.2
Fire fighting Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water.
Fire potential This chemical is flammable.
Hazards Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products Fire may produce irritating, corrosive and/or toxic gases.
NFPA Health 2
  Flammability 3  
  Reactivity 0  

Health.
Exposure limit(s) TLV: 5 ppm; 20 mg/m3 (skin) (ACGIH 1991-1992). OSHA PEL: TWA 100 ppm (410 mg/m3) NIOSH REL: TWA 1 ppm (4 mg/m3) NIOSH IDLH: 1600 ppm
Poison_Class 4
Exposure effects Prolonged or repeated skin contact may cause dermatitis. Chronic exposure produces peripheral neuropathy.
   Ingestion May cause irritation of the digestive tract. May cause central nervous system depression.
   Inhalation Causes respiratory tract irritation. May cause narcotic effects in high concentration. May cause drowsiness, unconsciousness, and central nervous system depression.
   Skin Causes mild skin irritation. May be absorbed through the skin in harmful amounts. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis.
   Eyes Causes mild eye irritation. Causes minor transient corneal injury.

First aid
 
   Ingestion If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number 1224
Response guide 127
Hazard class 3
Packing Group I; II; III  
USCG CHRIS Code MBK  
USCG Compatatibility Group 18 Ketones
Std. Transport # 4909242  
IMO Chemical Code 18
IMO Pollution Category D