Benzo[a]pyrene
- Benz(a)pyrene
- 3,4-Benzopyrene
- Benzo[def]chrysene
Benzo[a]pyrene | |
| |
| Formula | C20H12 |
| Structure | |
| Description | Pale yellow monoclinic needles from benzene & methanol. Faint aromatic odor. |
| Uses | Used extensively as a positive control in a variety of laboratory mutagenicity & carcinogenicity short-term tests. |
| Registry Numbers and Inventories. | |
| CAS | 50-32-8 |
| EC (EINECS/ELINCS) | 200-028-5 |
| EC Index Number | 601-032-00-3 |
| EC Class | Carcinogenic Category 2; Mutagenic Category 2; Toxic for reproduction Category 2; Dangerous for the Environment |
| RTECS | DJ3675000 |
| RTECS class | Tumorigen; Mutagen; Reproductive Effector; Primary Irritant |
| UN (DOT) | 2811 |
| Merck | 12,1134 |
| Beilstein/Gmelin | 1911333 |
| Beilstein Reference | 4-05-00-02687 |
| RCRA | U022 |
| Swiss Giftliste 1 | G-1248 |
| Canada DSL/NDSL | DSL |
| US TSCA | Listed |
| New Zealand | Listed |
| Properties. | |
| Formula | C20H12 |
| Formula mass | 252.32 |
| Melting point, °C | 176 - 178 |
| Boiling point, °C | 495 |
| Vapor pressure, mmHg | 2E-9 (25 C) |
| Vapor density (air=1) | 8.7 |
| Density | 1.351 g/cm3 |
| Solubility in water | 3 mg/L |
| Partition coefficient, pKow | 6.12 |
| Heat of fusion | 15.1 kJ/mol |
| Heat of vaporization | 73.4 kJ/mol |
| Hazards and Protection. | |
| Storage | Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. |
| Handling | Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. |
| Protection | Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. |
| Respirators | A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions. |
| Small spills/leaks | Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. |
| Stability | Stable under normal temperatures and pressures. |
| Incompatibilities | Strong oxidizing agents. |
| Decomposition | Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, acrid smoke and fumes. |
| Fire. | ||||
| Flash Point,°C | 228 | |||
| Fire fighting | Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam. | |||
| Fire potential | This material is nonflammable | |||
| Hazards | Contact with metals may evolve flammable hydrogen gas. | |||
| Combustion products | Fire may produce irritating, corrosive and/or toxic gases. | |||
| NFPA | Health | 0 | ||
| Flammability | 1 | |||
| Reactivity | 0 | |||
| Health. | |
| Exposure limit(s) | TLV: ppm; mg/m3 A2 (ACGIH 1997). MAK: TRK List 0.002 mg/m3; (1996) |
| Carcinogin | G-A2, I-2A, N-2, CP65 |
| Poison_Class | 1* |
| Exposure effects | May cause cancer in humans. |
| Ingestion | May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. |
| Inhalation | May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. |
| Skin | May cause skin irritation. |
| Eyes | May cause eye irritation. |
First aid |
|
| Ingestion | Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. |
| Inhalation | Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. |
| Skin | Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. |
| Eyes | Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. |
| Transport. | ||
| UN number | 2811 | |
| Response guide | 154 | |
| Hazard class | 6.1 | |
| Packing Group | I; II; III | |
| USCG CHRIS Code | BPY | |
| Std. Transport # | 4963340 | |