Bromacil

  • 5-Bromo-3-sec-butyl-6-methyluracil
  • 5-Bromo-6-methyl-3-(1-methylpropyl)uracil
  • Herbicide 976
  • Hyvar X
  • Hyvarex
Formula C9H13BrN2O2
Structure
Description Colorless to white odorless crystalline solid. Commercially available as a wettable powder or in liquid formulations.
Uses Herbicide.

Registry Numbers and Inventories.
CAS 314-40-9
EC (EINECS/ELINCS) 206-245-1
RTECS YQ9100000
RTECS class Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector
Merck 12,1402
Beilstein/Gmelin 647896
Beilstein Reference 5-24-07-00040
EPA OPP 12301
Swiss Giftliste 1 G-4479
Canada DSL/NDSL DSL
Austrailia AICS Listed
New Zealand Listed
Japan ENCS (MITI) Listed
Korea ECL Listed

Properties.
Formula C9H13BrN2O2
Formula mass 261.12
Melting point, °C 158 - 159
Boiling point, °C 411
Vapor pressure, mmHg 3E-7
Density 1.55 g/cm3 (20 C)
Solubility in water 800 mg/L
pKa/pKb 9.30 (pKa)
Partition coefficient, pKow 2.11

Hazards and Protection.
Storage Store in cool, dry place. Exposure of water-soluble formulations to air can cause some loss of water solubility.
Handling All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection Wear appropriate personal protective clothing to prevent skin contact.
Respirators Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability Stable up to MP and slowly sublimes @ temperature just below its MP active ingredient is chemically stable under normal storage conditions stable in aqueous bases. Slowly decomposed by concentrated acids.
Incompatibilities Strong oxidizing agents.
Decomposition When heated to decomposition it emits very toxic fumes of hydrogen bromide and nitrogen oxides.

Fire.
Fire fighting Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.
Fire potential Active ingredient and dry formulations are non-flammable; the liquid formulation (hyvar-xl) is a combustible mixture which should be kept away from heat and open flame.

Health.
Exposure limit(s) NIOSH REL: TWA 1 ppm (10 mg/m3)
Poison_Class 4
Exposure effects
   Ingestion Nausea, vomiting, and diarrhea may be noted following ingestion.
   Inhalation Symptoms: irritation eyes, skin, upper respiratory system; in animals: thyroid injury Target Organs: Eyes, skin, respiratory system, thyroid.
   Skin Cyanosis unresponsive to oxygen therapy may be noted in patients with methemoglobinemia due to absorption of excessive amounts of these agents.
   Eyes See inhalation.

First aid		  
   Ingestion Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended.
   Inhalation If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.