Captafol
- N-(1,1,2,2-Tetrachloroethylthio)cyclohex-4-ene-1,2-dicarboximide
- 3a,4,7,7a-Tetrahydro-N-(1,1,2,2-tetrachloroethanesulphenyl)phthalimide
- Difolitan
Captafol | |
| |
| Formula | C10H9Cl4NO2S |
| Structure | |
| Description | White, solid. Slight, characteristic pungent odor. |
| Uses | Fungicide. |
| Registry Numbers and Inventories. | |
| CAS | 2425-06-1 |
| EC (EINECS/ELINCS) | 219-363-3 |
| EC Index Number | 613-046-00-7 |
| EC Class | Carcinogenic Category 2; Sensitising; Dangerous for the Environment |
| RTECS | GW4900000 |
| RTECS class | Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector |
| UN (DOT) | 2773 |
| Merck | 12,1814 |
| Beilstein/Gmelin | 1543712 |
| Beilstein Reference | 5-21-10-00136 |
| EPA OPP | 81702 |
| Swiss Giftliste 1 | G-2675 |
| Austrailia AICS | Listed |
| New Zealand | Listed |
| Japan ENCS (MITI) | Listed |
| Korea ECL | Listed |
| Properties. | |
| Formula | C10H9Cl4NO2S |
| Formula mass | 349.06 |
| Melting point, °C | 160 |
| Vapor density (air=1) | 12 |
| Solubility in water | Insoluble |
| Partition coefficient, pKow | 3.83 |
| Hazards and Protection. | |
| Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. |
| Handling | All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
| Protection | Wear appropriate protective gloves, clothing and goggles. |
| Respirators | Wear positive pressure self-contained breathing apparatus (SCBA). |
| Small spills/leaks | Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. |
| Stability | Slowly hydrolyzed in aqueous emulsion or suspension. Rapidly hydrolyzed in acidic and alkaline media. Decomposes slowly at the melting point. |
| Incompatibilities | Incompatible with highly alkaline materials. Avoid contact with acids, acid vapors, strong oxidizers. |
| Decomposition | When heated to decomposition it emits very toxic fumes of hydrogen chloride, oxides of nitrogen and oxides of sulfur. |
| Fire. | ||||
| Fire fighting | Use method most appropriate to fight surrounding fire. | |||
| Fire potential | Non-Combustible | |||
| Combustion products | Fire may produce irritating, corrosive and/or toxic gases. | |||
| Health. | |
| Exposure limit(s) | TLV: ppm; 0.1 mg/m3 (skin) (ACGIH 1993-1993). NIOSH REL: Ca TWA 0.1 mg/m3 skin See Appendix A NIOSH IDLH: Potential occupational carcinogen |
| Carcinogin | I-2A, CP65 |
| Poison_Class | 4 |
| Exposure effects | The phthalimide fungicides contain the phthalimide moiety in common with phthalidomide, a known human teratogen. Captan has been teratogenic, fetotoxic, and/or embryotoxic in a variety of rodent species and caused stillbirths in dogs. Folpet was teratogenic in rabbits, chicks, and hamsters. Captafol has been embryo- or fetotoxic in experimental animals. <br>Captan, folpet, and captafol have all induced testicular degeneration in laboratory animals. |
| Ingestion | Nausea, vomiting, and diarrhea may follow ingestion. |
| Inhalation | Folpet is a respiratory tract irritant and can produce occupational asthma. |
| Skin | Irritant and allergic contact dermatitis have been reported with captan, folpet, and captafol. |
| Eyes | Folpet is an irritant of the eyes and mucous membranes. |
First aid |
|
| Ingestion | Seek medical assistance. |
| Inhalation | Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult. |
| Skin | Remove and isolate contaminated clothing and shoes. Remove material from skin immediately. Immediately flush with running water for at least 20 minutes. For minor skin contact, avoid spreading material on unaffected skin. |
| Eyes | Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. |
| Transport. | ||
| UN number | 2773 | |
| Response guide | 151 | |
| Hazard class | 6.1 | |