Chloroprene
- Chlorobutadiene
- 2-Chloro-1,3-butadiene
- 2-Chlorobuta-1,3-diene
Chloroprene | |
| |
| Formula | C4H5Cl |
| Structure | |
| Description | A clear colorless liquid. |
| Uses | Used as a chemical intermediate in the manufacture of artificial rubber. |
| Registry Numbers and Inventories. | |
| CAS | 126-99-8 |
| EC (EINECS/ELINCS) | 204-818-0 |
| EC Index Number | 602-036-00-8 |
| EC Class | Highly flammable; Harmful; Irritant |
| RTECS | EI9625000 |
| RTECS class | Tumorigen; Mutagen; Reproductive Effector; Primary Irritant |
| UN (DOT) | 1991 |
| Beilstein/Gmelin | 741875 |
| Beilstein Reference | 4-01-00984 |
| Swiss Giftliste 1 | G-1416 |
| Canada DSL/NDSL | DSL |
| US TSCA | Listed |
| Austrailia AICS | Listed |
| New Zealand | Listed |
| Japan ENCS (MITI) | Listed |
| Korea ECL | Listed |
| Properties. | |
| Formula | C4H5Cl |
| Formula mass | 88.54 |
| Melting point, °C | -130.0 |
| Boiling point, °C | 59.4 |
| Vapor pressure, mmHg | 215 |
| Vapor density (air=1) | 4.2 |
| Critical temperature | 261.7 |
| Density | 1.038 g/cm3 (20 C) |
| Solubility in water | 260 mg/L |
| Viscosity | 0.394 cp (25 C) |
| Refractive index | 1.4583 (20 C) |
| Partition coefficient, pKow | 2.01 |
| Heat of vaporization | 29.5 kJ/mol |
| Hazards and Protection. | |
| Storage | Oxidation.Inhibited by storage at less than -15C andor by the addition of antioxidants to the fresh distillate. Storage location should be close to laboratory where it is to be used, so that only small amounts need to be transported. Carcinogens should be kept in only one section of storage area, explosion-proof refrigerator or freezer as required. The area should be appropriately labeled. An inventory should be kept showing the quantity of carcinogen and date it was acquired. Facilities for dispensing should be contiguous to storage area. |
| Handling | All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
| Protection | Wear appropriate clothing to prevent any reasonable probability of skin contact. Wear eye protection to prevent any possibility of eye contact. |
| Respirators | Any self contained breathing apparatus with a full facepiece and operated in a pressure demand or other positive pressure mode or any supplied air respirator with a full facepiece and operated in a pressure demand or other positive pressure mode in combination with an auxiliary self contained breathing apparatus operated in pressure demand or other positive pressure mode. |
| Small spills/leaks | Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Attempt to stop leak if without undue personnel hazard. Use water spray to knock-down vapors. Land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash, cement powder, or commercial sorbents. Water spill: Use natural barriers or oil spill control booms to limit spill travel. Remove trapped material with suction hoses. |
| Stability | Polymerizes on standing. |
| Incompatibilities | Sensitive to exposure to air and light Sensitive to heat Mixtures with water, DMSO, 95% ethanol or acetone should be stable for 24 hours under normal lab conditions Incompatible with peroxides and other oxidizing agents Attacks some forms of plastics, rubbers and coatings Incompatible with strong oxidizing agents Attacks some forms of plastics, rubbers and coatings. |
| Decomposition | When heated to decomposition it emits toxic fumes of chlorine (cl-). |
| Fire. | ||||
| Flash Point,°C | -20 | |||
| Upper exp. limit, % | 20 | |||
| Lower exp. limit, % | 4 | |||
| Fire fighting | Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use foam, dry chemical, or carbon dioxide. | |||
| Fire potential | Component 1 is flammable. | |||
| Hazards | Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion and poison hazard indoors, outdoors or in sewers. | |||
| Combustion products | Decomposes yielding toxic fumes Dangerous when exposed to heat or flame | |||
| NFPA | Health | 2 | ||
| Flammability | 3 | |||
| Reactivity | 1 | |||
| Health. | |
| Exposure limit(s) | OSHA PEL: TWA 25 ppm (90 mg/m3) skin NIOSH REL: Ca C 1 ppm (3.6 mg/m3) 15-minute See Appendix A NIOSH IDLH: Potential occupational carcinogen 300 ppm |
| Carcinogin | I-2B, N-2, CP65 |
| Poison_Class | 4 |
| Exposure effects | Irritability, giddiness, and CNS depression may be seen. Chromosomal abnormalities and testicular damage have been reported. <br>Hydrocephalus and brain herniation have been seen in rat fetuses. <br>Physical and mental defects have been reported in children whose mothers worked in the polymerization area of a chloroprene rubber factory. |
| Ingestion | Nausea and anorexia may be seen. |
| Inhalation | Pneumonitis, leading to pulmonary edema, may be seen with inhalation of high concentrations. |
| Skin | Dermatitis may be seen after skin exposure. Alopecia has been reported in humans exposed to chloroprene. |
| Eyes | Inflammation of the eye, and focal necrosis of the cornea have been reported. Chloroprene is a lacrimator. |
First aid |
|
| Ingestion | DO NOT INDUCE VOMITING. Volatile chemicals have a high risk of being aspirated into the victim's lungs during vomiting which increases the medical problems. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital. |
| Inhalation | IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used. |
| Skin | IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. |
| Eyes | First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| Transport. | ||
| UN number | 1991 | |
| Response guide | 131 | |
| Hazard class | 3 (Forbidden for unstabilized) | |
| Packing Group | I | |
| USCG CHRIS Code | CRP | |
| Std. Transport # | 4907223 | |