Dimethyl acetamide
- N,N-Dimethylacetamide
- DMAC
- Acetic acid dimethylamide
Dimethyl acetamide | |
| |
| Formula | CH3CON(CH3)2 |
| Structure | |
| Description | Colorless liquid, weak ammonia or fish-like odor. |
| Uses | Solvent in industrial applications. |
| Registry Numbers and Inventories. | |
| CAS | 127-19-5 |
| EC (EINECS/ELINCS) | 204-826-4 |
| EC Index Number | 616-011-00-4 |
| EC Class | Toxic for reproduction Category 2; Harmful |
| EC Risk Phrase | R 61 20/21 |
| EC Safety Phrase | S 53 45 |
| RTECS | AB7700000 |
| RTECS class | Drug; Mutagen; Reproductive Effector; Primary Irritant |
| Merck | 13,3254 |
| Beilstein/Gmelin | 1737614 |
| Beilstein Reference | 4-04-00-00180 |
| Swiss Giftliste 1 | G-1554 |
| Canada DSL/NDSL | DSL |
| US TSCA | Listed |
| Austrailia AICS | Listed |
| New Zealand | Listed |
| Japan ENCS (MITI) | Listed |
| Korea ECL | Listed |
| Properties. | |
| Formula | C4H9NO |
| Formula mass | 87.12 |
| Melting point, °C | -20 |
| Boiling point, °C | 166.1 |
| Vapor pressure, mmHg | 10 (25 C) |
| Vapor density (air=1) | 3 |
| Saturation Concentration | 2600 ppm (0.26%) at 25 C (calculated) |
| Evaporization number | 172 (diethyl ether = 1), 0.138 (butyl acetate = 1) |
| Critical temperature | 385 |
| Critical pressure | 39.7 |
| Density | 0.937 g/cm3 (20 C) |
| Solubility in water | Miscible |
| Viscosity | 0.92 cp @ 25C |
| Surface tension | 34 g/s2 @ 20 C |
| Refractive index | 1.4373 (20 C) |
| Dipole moment | 3.8 D (20 C) |
| Dielectric constant | 37.8 (25 C) |
| Partition coefficient, pKow | -0.77 |
| Heat of fusion | 10.4 kJ/mol |
| Heat of vaporization | 49.7 kJ/mol |
| Heat of combustion | -2540 kJ/mol |
| Hazards and Protection. | |
| Storage | Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store in direct sunlight. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. |
| WHMIS | B3 Combustible liquid. Class D2B Toxic Material; Chronic Toxic Effects. |
| Handling | Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. |
| Protection | Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. |
| Respirators | Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. |
| Small spills/leaks | Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. |
| Disposal code | 1 |
| Stability | Stable under normal temperatures and pressures. |
| Incompatibilities | Ammonia, nonoxidizing mineral acids, strong acids, phenols, isocyanates, cresol, halogens, coatings, plastics, rubber, iron. |
| Decomposition | Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. |
| Fire. | ||||
| Flash Point,°C | 70 | |||
| Autoignition, °C | 354 | |||
| Upper exp. limit, % | 11.5 | |||
| Lower exp. limit, % | 1.7 | |||
| Fire fighting | Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Use foam, dry chemical, or carbon dioxide. | |||
| Fire potential | This chemical is combustible. | |||
| NFPA | Health | 2 | ||
| Flammability | 2 | |||
| Reactivity | 0 | |||
| Health. | |
| Exposure limit(s) | OSHA PEL: TWA 10 ppm (35 mg/m3) skin NIOSH REL: TWA 10 ppm (35 mg/m3) skin NIOSH IDLH: 300 ppm |
| Poison_Class | 3 |
| Exposure effects | Chronic ingestion may cause liver damage. May cause reproductive and fetal effects. |
| Ingestion | May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver damage. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May cause auditory and visual hallucinations, disorientation, sweating, and |
| Inhalation | Causes respiratory tract irritation. May cause effects similar to those described for ingestion. Aspiration may lead to pulmonary edema. Inhalation at high concentrations may cause CNS depression and asphixiation. |
| Skin | Causes skin irritation. May be absorbed through the skin. If absorbed, causes symptoms similar to those of ingestion. May cause cyanosis of the extremities. |
| Eyes | Causes eye irritation. May cause chemical conjunctivitis and corneal damage. |
First aid |
|
| Ingestion | Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. |
| Inhalation | Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. |
| Skin | Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. |
| Eyes | Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. |
| Transport. | ||
| USCG CHRIS Code | DLS | |
| USCG Compatatibility Group | 10 Amides | |
| HS Code | 2924 19 00 | |
| Std. Transport # | 4913246 | |
| IMO Chemical Code | 17 | |
| IMO Pollution Category | D | |
| IMO Hazard code | S | |