Disulfiram

Disulfiram
bis(Diethylthiocarbamoyl) disulfide Tetraethylthiuram disulfide Tetraethylthioperoxydicarbonic diamide
Formula	C₁₀H₂₀N₂S₄
Structure
Description	White or light gray, crystalline, slight odor.
Uses	alcohol aversive drug

Registry Numbers and Inventories.
CAS	97-77-8
EC (EINECS/ELINCS)	202-607-8
EC Index Number	006-079-00-8
EC Class	Harmful; Sensitising; Dangerous for the Environment
EC Risk Phrase	R 22 48/22 43 50/53
EC Safety Phrase	S 24 37 60 61
RTECS	JO1225000
RTECS class	Agricultural Chemical and Pesticide; Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Primary Irritant
UN (DOT)	3077
Merck	13,3399
Beilstein/Gmelin	1712560
Beilstein Reference	4-04-00-00398
RCRA	U403
Swiss Giftliste 1	G-1595
Canada DSL/NDSL	DSL
US TSCA	Listed
Austrailia AICS	Listed
New Zealand	Listed
Japan ENCS (MITI)	Listed
Korea ECL	Listed

Hazards and Protection.
Storage	Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed.
Handling	Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation.
Protection	Eyes: Wear safety glasses and chemical goggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators	Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks	Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability	Stable under normal temperatures and pressures.
Incompatibilities	Strong oxidizing agents.
Decomposition	Carbon monoxide, oxides of nitrogen, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C		177
Fire fighting		Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Fire potential		This material is probably combustible.

Health.
Exposure limit(s)	NIOSH REL: TWA 2 mg/m3
Poison_Class	3
Exposure effects	Increased respirations, elevated blood pressure, rapid heart rate and fever may occur. Abnormally low blood pressure may occur with severe overdose. Seizures and coma can be seen with overdose or ethanol interaction.
Ingestion	Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation	May cause respiratory tract irritation.
Skin	May cause skin irritation.
Eyes	May cause eye irritation.
First aid
Ingestion	If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation	Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin	Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes	Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.