Isopropylamine
- 2-Aminopropane
- 2-Propanamine
- 1-Methylethylamine
- sec-Propylamine
- 2-Propylamine
- Monoisopropylamine
Isopropylamine | |
| |
| Formula | (CH3)2CHNH2 |
| Structure | |
| Description | Clear, colorless liquid with an ammonia-like odor. |
| Uses | Solvent, intermediate in synthesis of rubber accelerators, pharmaceuticals, dyes, insecticides, bactericides, textile specialities, and surface-active agents, dehairing agent, solubilizer for 2,4-d acid. |
| Registry Numbers and Inventories. | |
| CAS | 75-31-0 |
| EC (EINECS/ELINCS) | 200-860-9 |
| EC Index Number | 612-007-00-1 |
| EC Class | Extremely flammable; Irritant |
| EC Risk Phrase | R 12 36/37/38 |
| EC Safety Phrase | S 16 26 29 |
| RTECS | NT8400000 |
| RTECS class | Tumorigen; Primary Irritant |
| UN (DOT) | 1221 |
| Merck | 13,5229 |
| Beilstein/Gmelin | 605259 |
| Beilstein Reference | 4-04-00-00504 |
| Swiss Giftliste 1 | G-1092 |
| Canada DSL/NDSL | DSL |
| US TSCA | Listed |
| Austrailia AICS | Listed |
| New Zealand | Listed |
| Japan ENCS (MITI) | Listed |
| Korea ECL | Listed |
| Properties. | |
| Formula | C3H9N |
| Formula mass | 59.11 |
| Melting point, °C | -101 |
| Boiling point, °C | 32.4 |
| Vapor pressure, mmHg | 580 (25 C) |
| Vapor density (air=1) | 2.04 |
| Saturation Concentration | 60.5% (20 C) |
| Critical temperature | 199 |
| Critical pressure | 44.8 |
| Density | 0.69 (g/cm3 (20 C) |
| Solubility in water | Miscible |
| Surface tension | 16.8 g/s2 (25 C) |
| Refractive index | 1.377 (20 C) |
| Dipole moment | 1.19 D |
| pKa/pKb | 3.37 (pKb) |
| Partition coefficient, pKow | 0.26 |
| Heat of vaporization | 28.36 kJ/mol |
| Heat of combustion | -2345.5 kJ/mol |
| Hazards and Protection. | |
| Storage | Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). Store in steel containers. |
| WHMIS | B2 E D1B |
| Handling | Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Ground and bond containers when transferring material. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. |
| Protection | Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. |
| Respirators | A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. |
| Small spills/leaks | Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Do not get water inside containers. A vapor suppressing foam may be used to reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces. |
| Disposal code | 5 |
| Stability | Stable under normal temperatures and pressures. |
| Incompatibilities | Strong oxidizing agents, strong acids, acid chlorides, acid anhydrides, perchloryl fluoride, 1-chloro-1,3-epoxypropane, aldehydes, epoxides (e.g. butyl glycidyl ether), halogenated agents, mineral acids, organic acids, sodium hypochlorite, calcium hypochlorite, copper, aluminum, zinc, galvanized surfaces, peroxides. |
| Decomposition | Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, ammonia, nitric acid. |
| Fire. | ||||
| Flash Point,°C | -37 | |||
| Autoignition, °C | 402 | |||
| Upper exp. limit, % | 10.4 | |||
| Lower exp. limit, % | 2.0 | |||
| Fire fighting | Evacuate area and fight fire from a safe distance. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Approach fire from upwind to avoid hazardous vapors and toxic decomposition products. Extinguish with water spray, dry chemical, alcohol resistant foam, or carbon dioxide. Water may be ineffective because it will not cool material below its flash point. | |||
| Fire potential | Extremely flammable liquid and vapor. Vapor may cause flash fire. | |||
| Hazards | Burning isopropylamine is difficult to control because of the ease of reignition of the vapor. Vapors are heavier than air and may travel to a source of ignition and flash back. Containers may explode. | |||
| Combustion products | Toxic oxides of nitrogen may form in fire. | |||
| NFPA | Health | 3 | ||
| Flammability | 4 | |||
| Reactivity | 0 | |||
| Health. | |
| Exposure limit(s) | OSHA PEL: TWA 5 ppm (12 mg/m3) NIOSH REL: See Appendix D NIOSH IDLH: 750 ppm |
| Poison_Class | 3 |
| Exposure effects | Prolonged or repeated skin contact may cause dermatitis. |
| Ingestion | Harmful if swallowed. Causes gastrointestinal tract burns. May cause central nervous system effects. |
| Inhalation | Harmful if swallowed. Causes gastrointestinal tract burns. May cause central nervous system effects. |
| Skin | Harmful if absorbed through the skin. Causes severe skin irritation and burns. |
| Eyes | Low vapor concentrations may cause a temporary visual disturbance known as 'blue haze' or 'halo vision'. Causes eye irritation and burns. May cause tearing, conjunctivitis and corneal edema when vapor is absorbed into the tissue of the eye. Direct contact with liquid may cause blindness or permanent eye damage. |
First aid |
|
| Ingestion | Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. |
| Inhalation | Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. |
| Skin | Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes. |
| Eyes | Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes). |
| Transport. | ||
| UN number | 1221 | |
| Response guide | 132 | |
| Hazard class | 3 | |
| Packing Group | I | |
| USCG CHRIS Code | IPP | |
| USCG Compatatibility Group | 7 Aliphatic amines | |
| HS Code | 2921 19 30 | |
| Std. Transport # | 4931311 | |
| IMO Chemical Code | 17 | |
| IMO Pollution Category | C | |
| IMO Hazard code | S/P | |