Methyl isobutyl ketone
- 4-Methyl-2-pentanone
- Isobutyl methyl ketone
- Hexone
- 4-Methylpentan-2-one
Methyl isobutyl ketone | |
| |
| Formula | (CH3)2CHCH2COCH3 |
| Structure | |
| Description | Clear, colorless liquid with a sweet, camphor-like odor. |
| Uses | Solvent for vinyl, epoxy, acrylic and natural resins. Solvent for nitrocellulose and dyes. |
| Registry Numbers and Inventories. | |
| CAS | 108-10-1 |
| EC (EINECS/ELINCS) | 203-550-1 |
| EC Index Number | 606-004-00-4 |
| EC Class | Highly flammable; Harmful; Irritant; Repeated exposure may cause skin dryness or cracking |
| EC Risk Phrase | R 11 20 36/37 66 |
| EC Safety Phrase | S 9 16 29 |
| RTECS | SA9275000 |
| RTECS class | Tumorigen; Reproductive Effector; Human Data; Primary Irritant |
| UN (DOT) | 1245 |
| Merck | 13,5227 |
| Beilstein/Gmelin | 605399 |
| Beilstein Reference | 4-01-00-03305 |
| RCRA | U161 |
| EPA OPP | 44105 |
| Swiss Giftliste 1 | G-2468 |
| Canada DSL/NDSL | DSL |
| US TSCA | Listed |
| Austrailia AICS | Listed |
| New Zealand | Listed |
| Japan ENCS (MITI) | Listed |
| Korea ECL | Listed |
| Properties. | |
| Formula | C6H12O |
| Formula mass | 100.16 |
| Melting point, °C | -84 |
| Boiling point, °C | 117.4 |
| Vapor pressure, mmHg | 20 (25 C) |
| Vapor density (air=1) | 3.45 |
| Saturation Concentration | 0.79% @ 20 C |
| Evaporization number | 1.6 (butyl acetate=1) |
| Critical temperature | 301 |
| Critical pressure | 32.27 |
| Density | 0.801 g/cm3 |
| Solubility in water | 20 g/L |
| Viscosity | 0.00542 g/(cm s) |
| Surface tension | 23.6 g/s2 |
| Refractive index | 1.396 (20 C) |
| Dipole moment | 13.11 D (20 C) |
| Dielectric constant | 13.1 (20 C) |
| Partition coefficient, pKow | 1.31 |
| Heat of vaporization | 40.56 kJ/mol |
| Heat of combustion | -3697 kJ/mol |
| Hazards and Protection. | |
| Storage | Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. |
| WHMIS | B2 |
| Handling | Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with skin and eyes. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. |
| Protection | Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. |
| Respirators | Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. |
| Small spills/leaks | Avoid runoff into storm sewers and ditches which lead to waterways. Wear a self contained breathing apparatus and appropriate Personal protection. (See Exposure Controls, Personal Protection section). Scoop up with a nonsparking tool, then place into a suitable container for disposal. Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. Provide ventilation. |
| Disposal code | 1 |
| Stability | Stable at room temperature in closed containers under normal storage and handling conditions. Can form and accumulate peroxides which may explode when subjected to heat or shock. This material is most hazardous when peroxide levels are concentrated by distillation or evaporation. |
| Incompatibilities | Aldehydes, nitric acid, perchloric acid, strong oxidizers, strong reducing agents. Violent reaction with potassium tert-butoxide. |
| Decomposition | Carbon monoxide, carbon dioxide. |
| Fire. | ||||
| Flash Point,°C | 14 | |||
| Autoignition, °C | 448 | |||
| Upper exp. limit, % | 8.0 | |||
| Lower exp. limit, % | 1.2 | |||
| Fire fighting | Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Water may be ineffective. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out. | |||
| Fire potential | Flammable liquid and vapor. | |||
| Hazards | Vapor is heavier than air (vapor-air density at 100 deg f, 1:1) and may travel considerable distance to source of ignition and flash back. Containers may explode in the heat of a fire. May polymerize explosively when involved in a fire. | |||
| Combustion products | Irritating vapors are generated when heated. | |||
| NFPA | Health | 2 | ||
| Flammability | 3 | |||
| Reactivity | 0 | |||
| Health. | |
| Exposure limit(s) | OSHA PEL: TWA 100 ppm (410 mg/m3) NIOSH REL: TWA 50 ppm (205 mg/m3) ST 75 ppm (300 mg/m3) NIOSH IDLH: 500 ppm |
| Poison_Class | 4 |
| Exposure effects | Prolonged skin contact may defat the skin and produce dermatitis. Based on animal studies, chronic exposure may affect liver and kidneys. |
| Ingestion | May produce abdominal pain, nausea. Aspiration into lungs can produce severe lung damage and is a medical emergency. Other symptoms expected to parallel inhalation. |
| Inhalation | Causes irritation to the nose and throat. Concentrations above the TLV may cause headache, dizziness, nausea, shortness of breath, and vomiting. Higher concentrations may cause central nervous system depression and unconsciousness. |
| Skin | Causes irritation to skin. Symptoms include redness, itching, and pain. |
| Eyes | Vapors may cause eye irritation. May cause painful sensitization to light. Splashes produces irritation, tearing, and burning pain. |
First aid |
|
| Ingestion | If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. |
| Inhalation | Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. |
| Skin | Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse. |
| Eyes | Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. |
| Transport. | ||
| UN number | 1245 | |
| Response guide | 127 | |
| Hazard class | 3 | |
| Packing Group | II | |
| USCG CHRIS Code | MIK | |
| USCG Compatatibility Group | 18 Ketones | |
| HS Code | 2914 13 00 | |
| Std. Transport # | 4909244 | |
| IMO Chemical Code | 18 | |
| IMO Pollution Category | D | |