N-Methyl-2-pyrrolidone
- N-Methylpyrrolidone
- 1-Methyl-2-pyrrolidone
- 1-Methyl-2-pyrrolidinone
N-Methyl-2-pyrrolidone | |
| |
| Formula | C5H9NO |
| Structure | |
| Description | Colorless liquid, amine-like odor, hygroscopic. |
| Uses | Solvent for resins, acetylene, etc., Pigment dispersant, petroleum processing, spinning agent for polyvinyl chloride, microelectronics industry plastic solvent applications, intermediate. |
| Registry Numbers and Inventories. | |
| CAS | 872-50-4 |
| EC (EINECS/ELINCS) | 212-828-1 |
| EC Index Number | 606-021-00-7 |
| EC Class | Irritant |
| EC Risk Phrase | R 36/38 |
| EC Safety Phrase | S 41 |
| RTECS | UY5790000 |
| RTECS class | Tumorigen; Mutagen; Reproductive Effector; Primary Irritant |
| UN (DOT) | 1760 |
| Merck | 12,6197 |
| Beilstein/Gmelin | 106420 |
| Beilstein Reference | 5-21-06-00321 |
| Swiss Giftliste 1 | G-2530 |
| Canada DSL/NDSL | DSL |
| US TSCA | Listed |
| Austrailia AICS | Listed |
| New Zealand | Listed |
| Japan ENCS (MITI) | Listed |
| Korea ECL | Listed |
| Properties. | |
| Formula | C5H9NO |
| Formula mass | 99.13 |
| Melting point, °C | -24 |
| Boiling point, °C | 202 |
| Vapor pressure, mmHg | 6.5 (25 C) |
| Vapor density (air=1) | 3.4 |
| Saturation Concentration | 380 ppm at 20 C (calculated) |
| Evaporization number | 0.06 (butyl acetate = 1) |
| Critical temperature | 451 |
| Critical pressure | 47.2 |
| Density | 1.033 g/cm3 (20 C) |
| Solubility in water | Soluble |
| Viscosity | 1.65 cp at 25C |
| Surface tension | 40.7 g/s2 |
| Refractive index | 1.4684 (20 C) |
| Dipole moment | 4.1 D(20 C) |
| Dielectric constant | 33 (25 C) |
| Partition coefficient, pKow | -0.54 |
| Heat of fusion | 9.11 kJ/mol |
| Heat of vaporization | 5336 kJ/mol |
| Heat of combustion | -2994 kJ/mol |
| Hazards and Protection. | |
| Storage | Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture. Store protected from light. |
| WHMIS | B3 D2B |
| Handling | Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Store protected from light. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. |
| Protection | Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. |
| Respirators | A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. |
| Small spills/leaks | Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. |
| Disposal code | 5 |
| Stability | Stable at room temperature in closed containers under normal storage and handling conditions. Light sensitive. |
| Incompatibilities | Strong oxidizing agents, strong acids, sulfur, carbon disulfide, chlorinating agents, moisture. |
| Decomposition | Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. |
| Fire. | ||||
| Flash Point,°C | 91 | |||
| Autoignition, °C | 245 | |||
| Upper exp. limit, % | 9.5 | |||
| Lower exp. limit, % | 1.3 | |||
| Fire fighting | Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Combustible Liquid. Toxic oxides of nitrogen may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use extinguishing media most appropriate for the surrounding fire. Cool containers with flooding quantities of water until well after fire is out. | |||
| Fire potential | Combustible when exposed to heat, open flame, or powerful oxidizers. | |||
| Hazards | Contact with metals may evolve flammable hydrogen gas. | |||
| Combustion products | Toxic oxides of nitrogen may be formed in fire. | |||
| NFPA | Health | 2 | ||
| Flammability | 2 | |||
| Reactivity | 0 | |||
| Health. | |
| Exposure limit(s) | MAK: 20 ppm; 80 mg/m3; skin (1996). |
| Poison_Class | 5 |
| Exposure effects | Prolonged or repeated skin contact may cause dermatitis. May cause reproductive and fetal effects. Laboratory experiments have resulted in mutagenic effects. |
| Ingestion | May cause gastrointestinal irritation with nausea, vomiting and diarrhea. |
| Inhalation | Causes respiratory tract irritation. May cause abdominal pain, nausea, vomiting, and inflammation of the gums and mouth. Inhalation of vapors in confined spaces or when hot may cause drowsiness, dizziness, headache, nausea, or lung irritation. |
| Skin | Causes skin irritation. May be absorbed through the skin. Repeated or prolonged exposure may cause drying and cracking of the skin. |
| Eyes | Causes moderate eye irritation. May cause temporary corneal clouding. |
First aid |
|
| Ingestion | If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. |
| Inhalation | Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. |
| Skin | Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. |
| Eyes | Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. |
| Transport. | ||
| UN number | 1760 | |
| Response guide | 154 | |
| Hazard class | 8 | |
| Packing Group | I; II; III | |
| USCG CHRIS Code | MPY | |
| USCG Compatatibility Group | 9 Aromatic amines | |
| HS Code | 2933 79 00 | |
| Std. Transport # | 4915473 | |
| IMO Chemical Code | 18 | |
| IMO Pollution Category | D | |