Nicotine
- 3-(1-methyl-2-pyrrolidinyl)pyridine
- (S)-3-(1-Methylpyrrolidin-2-yl)pyridine
- 1-Methyl-2-(3-pyridyl)pyrrolidine
- beta-Pyridyl-alpha-n-methylpyrrolidine
Nicotine | |
| |
| Formula | C10H14N2 |
| Structure | |
| Description | Colorless to pale yellow, oily liquid, turns brown on exposure to air and light. Develops fish-like odor when warm. Hygrosopic. |
| Uses | Insecticide (former use), fumigant (former use). |
| Registry Numbers and Inventories. | |
| CAS | 54-11-5 |
| EC (EINECS/ELINCS) | 200-193-3 |
| EC Index Number | 614-001-00-4 |
| EC Class | Very toxic; Toxic; Dangerous for the Environment |
| EC Risk Phrase | R 25 27 51/53 |
| EC Safety Phrase | S 36/37 45 61 |
| RTECS | QS5250000 |
| RTECS class | Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector; Human Data; Natural Product |
| UN (DOT) | 1654 |
| Merck | 12,6611 |
| Beilstein/Gmelin | 82109 |
| Beilstein Reference | 5-23-06-00064 |
| RCRA | P075 |
| EPA OPP | 56702 |
| Swiss Giftliste 1 | G-2057 |
| Canada DSL/NDSL | DSL |
| US TSCA | Listed |
| Austrailia AICS | Listed |
| New Zealand | Listed |
| Japan ENCS (MITI) | Listed |
| Korea ECL | Listed |
| Properties. | |
| Formula | C10H14N2 |
| Formula mass | 162.24 |
| Melting point, °C | -79 |
| Boiling point, °C | 247 |
| Vapor pressure, mmHg | 0.03 (25 C) |
| Vapor density (air=1) | 5.61 |
| Saturation Concentration | 56 ppm (0.0056%) at 20 C (calculated) |
| Density | 1.01 g/cm3 (25 C) |
| Solubility in water | Soluble |
| Surface tension | 38.61 g/s2 |
| Refractive index | 1.5282 (20 C) |
| pKa/pKb | 6.00 (pKb) |
| Partition coefficient, pKow | 1.17 |
| Heat of vaporization | 48.1 kJ/mol |
| Heat of combustion | -5910 kJ/mol |
| Hazards and Protection. | |
| Storage | Keep away from sources of ignition. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from strong acids. |
| Handling | Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Do not reuse this container. Do not get on skin or in eyes. Do not ingest or inhale. |
| Protection | Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear impervious gloves. Clothing: Wear appropriate protective clothing to prevent skin exposure. |
| Respirators | Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. |
| Small spills/leaks | Avoid runoff into storm sewers and ditches which lead to waterways. Wear a self contained breathing apparatus and appropriate Personal protection. (See Exposure Controls, Personal Protection section). Remove all sources of ignition. Absorb spill using an absorbent, non-combustible material such as earth, sand, or vermiculite. |
| Disposal code | 9 |
| Stability | Stable at room temperature in closed containers under normal storage and handling conditions. |
| Incompatibilities | Strong acids, strong oxidizers. |
| Decomposition | Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen. |
| Fire. | ||||
| Flash Point,°C | 101 | |||
| Autoignition, °C | 240 | |||
| Upper exp. limit, % | 4 | |||
| Lower exp. limit, % | 0.7 | |||
| Fire fighting | Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Can form explosive mixtures at temperatures above the flashpoint. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam. Water or foam may cause frothing. | |||
| Fire potential | Slightly flammable. Flammable if preheated. | |||
| Hazards | There is a moderate explosion hazard when exposed to heat or flame. When heated to decomposition, it emits nitrogen oxides, carbon monoxide and other highly toxic fumes. Avoid oxidizing materials. Stable under normal conditions. Avoid heat or flames. | |||
| Combustion products | When heated, emits highly toxic fumes. | |||
| NFPA | Health | 3 | ||
| Flammability | 1 | |||
| Reactivity | 0 | |||
| Health. | |
| Exposure limit(s) | TLV: 0.5 mg/m3 (as TWA) (skin) (ACGIH 1996). MAK: 0.07 ppm; 0.5 mg/m3; H (1996). OSHA PEL: TWA 0.5 mg/m3 skin NIOSH REL: TWA 0.5 mg/m3 skin NIOSH IDLH: 5 mg/m3 |
| Poison_Class | 1 |
| Exposure effects | May cause digestive tract and cardiac disturbances. |
| Ingestion | May be fatal if swallowed. May cause adverse effects of the musculature. May cause severe digestive tract irritation with abdominal pain, nausea, vomiting and diarrhea. May cause tremors and convulsions. May cause muscle paralysis, respiratory failure, and possible death. Exposure causes initial nervous system stimulation followed by severe CNS depression. May cause ataxia and |
| Inhalation | May cause effects similar to those described for ingestion. |
| Skin | May cause skin irritation. May be fatal if absorbed through the skin. |
| Eyes | May cause eye irritation. |
First aid |
|
| Ingestion | If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately. |
| Inhalation | Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. |
| Skin | Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes. |
| Eyes | Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. |
| Transport. | ||
| UN number | 1654 | |
| Response guide | 151 | |
| Hazard class | 6.1 | |
| Packing Group | II | |
| USCG CHRIS Code | NIC | |
| HS Code | 2939 99 90 | |
| Std. Transport # | 4921785 4925274 | |