Toluene 2,4-diisocyanate

  • 2,4-Diisocyanatotoluene
  • 2,4-Tolyenediisocyanate
  • TDI
  • 4-Methyl-m-phenylene diisocyanate
  • 2,4-Diisocyanato-1-methylbenzene
Formula 2,4-(NCO)C6H3CH3
Structure
Description Water white to pale yellow liquid or crystals with a sweet, fruity, pungent odor. Darkens on exposure to sunlight.
Uses Chemical intermediate.

Registry Numbers and Inventories.
CAS 584-84-9
EC (EINECS/ELINCS) 209-544-5
EC Index Number 615-006-00-4
EC Class Carcinogenic Category 3; Very toxic; Irritant; Sensitising; Dangerous for the Environment
EC Risk Phrase R 26 36/37/38 40 42/43 52/53
EC Safety Phrase S 23 36/37 45 61
RTECS CZ6300000
RTECS class Tumorigen; Mutagen; Human Data; Primary Irritant
UN (DOT) 2078
Merck 12,9668
Beilstein/Gmelin 744602
Beilstein Reference 4-13-00-00243
RCRA U223
Swiss Giftliste 1 G-3610
Canada DSL/NDSL DSL
US TSCA Listed
Austrailia AICS Listed
New Zealand Listed
Japan ENCS (MITI) Listed
Korea ECL Listed

Odor Threshold Odor threshold 0.4-2.14 ppm
Properties.
Formula C9H6N2O2
Formula mass 174.16
Melting point, °C 21
Boiling point, °C 251
Vapor pressure, mmHg 0.008 (25 C)
Saturation Concentration 33 ppm (25 C)
Critical temperature 488
Critical pressure 29.5
Density 1.218 g/cm3 (20 C)
Solubility in water Insoluble
Viscosity 0.0027 cp (25 C)
Surface tension 25 g/s2
Refractive index 1.5678 (20 C)
Dipole moment 2.52 D (20 C)
Heat of vaporization 40.61 kJ/mol
Heat of combustion -4126 kJ/mol

Hazards and Protection.
Storage Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture. Store under an inert atmosphere.
WHMIS D1A D2A D2B
Handling Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid breathing dust, vapor, mist, or gas. Do not allow contact with water.
Protection Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
Small spills/leaks Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Provide ventilation. Do not expose spill to water. Do not get water inside containers.
Disposal code 9
Stability Stable under normal temperatures and pressures.
Incompatibilities Alcohols - strong bases - amines - acids - heat - light - strong oxidizing agents - moisture.
Decomposition Hydrogen cyanide, nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C 127
Autoignition, °C > 620
Upper exp. limit, % 9.5
Lower exp. limit, % 0.9
Fire fighting Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For large fires, use water spray or fog. Do NOT get water inside containers. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out. For small fires, use dry chemical or carbon dioxide.
Fire potential Slightly flammable. Combustible when exposed to heat or flame.
Hazards When heated to decomposition it emits very toxic fumes of cyanide and nitrogen oxides. Reacts violently with amines, alcohol, bases and warm water causing fire and explosion hazards. Avoid strong oxidizers, water, acids, bases, amines, etc., cause foam and splatter. Avoid heating. Hazardous polymerization may occur. Concentrated alkaline compound such as sodium hydroxide or tertiary amines may cause run-away polymerization. Slow, not hazardous polymerization may occur above 235F.
Combustion products Toxic oxides of nitrogen are produced during combustion of this material.
NFPA Health 3
  Flammability 1  
  Reactivity 1  

Health.
Exposure limit(s) NIOSH REL: Ca See Appendix A OSHA PEL: C 0.02 ppm (0.14 mg/m3) IDLH Ca [2.5 ppm]
Carcinogin I-2B, N-2
Poison_Class 2
Exposure effects Acute exposures may produce headache, insomnia, euphoria, ataxia, anxiety neurosis with depression, paranoid tendencies, or impotence. No data were available to assess the teratogenic potential of this agent. <br>No data were available to assess the potential effects of exposure to this agent during pregnancy or lactation.
   Ingestion Causes gastrointestinal tract irritation.
   Inhalation May be fatal if inhaled. Causes respiratory tract irritation.
   Skin Causes skin irritation.
   Eyes Causes eye irritation.

First aid		  
   Ingestion Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
   Skin Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Get medical aid if symptoms occur.
   Eyes Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number 2078
Response guide 156
Hazard class 6.1
Packing Group II  
USCG CHRIS Code TDI  
USCG Compatatibility Group 12 Isocyanates
HS Code 2929 10 10  
IMO Pollution Category C
IMO Hazard code S/P