Tolylene 2,6-diisocyanate
- 2-Methyl-1,3-phenylene diisocyanate
- 2,6-Diisocyanatotoluene
- 2,6-Toluylene diisocyanate
- 2-Methyl-m-phenylene isocyanate
- Toluene 2,6-diisocyanate
- Isocyanic acid, 2-methyl-m-phenylene ester
Tolylene 2,6-diisocyanate | |
| |
| Formula | C9H6N2O2 |
| Structure | |
| Description | Clear, colorless or pale yellow liquid with a characteristic pungent odor. |
| Uses | Peparation of polyurethane foams, elastomers and coatings, as a cross-linking agent for nylon-6, and as a hardener in polyurethane adhesives and finishes. |
| Registry Numbers and Inventories. | |
| CAS | 91-08-7 |
| EC (EINECS/ELINCS) | 202-039-0 |
| EC Index Number | 615-006-00-4 |
| EC Class | Carcinogenic Category 3; Very toxic; Irritant; Sensitising; Dangerous for the Environment |
| EC Risk Phrase | R 26 36/37/38 40 42/43 52/53 |
| EC Safety Phrase | S 23 36/37 45 61 |
| RTECS | CZ6310000 |
| RTECS class | Tumorigen; Mutagen; Human Data |
| UN (DOT) | 2078 |
| Beilstein/Gmelin | 2211546 |
| Beilstein Reference | 4-13-00-00259 |
| Swiss Giftliste 1 | G-2083 |
| Canada DSL/NDSL | DSL |
| US TSCA | Listed |
| Austrailia AICS | Listed |
| New Zealand | Listed |
| Japan ENCS (MITI) | Listed |
| Korea ECL | Listed |
| Properties. | |
| Formula | C9H6N2O2 |
| Formula mass | 174.16 |
| Melting point, °C | 13 |
| Boiling point, °C | 246 - 247 |
| Vapor pressure, mmHg | 0.02 (25 C) |
| Vapor density (air=1) | 6.0 |
| Saturation Concentration | Approx. 21 ppm at 20 C (calculated) |
| Density | 1.22 g/cm3 (20 C) |
| Solubility in water | Insoluble |
| Refractive index | 1.571 (20 C) |
| Partition coefficient, pKow | 3.47 |
| Heat of vaporization | 48.6 kJ/mol |
| Hazards and Protection. | |
| Storage | Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). Store protected from moisture. |
| WHMIS | D1A D2A D2B |
| Handling | Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Do not allow contact with water. Wash clothing before reuse. Keep from contact with moist air and steam. |
| Protection | Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. |
| Respirators | Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. |
| Small spills/leaks | Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Provide ventilation. Do not get water inside containers. |
| Stability | Stable at room temperature in closed containers under normal storage and handling conditions. |
| Incompatibilities | Moisture, acids, alcohols, amines, strong bases, oxidizing agents. |
| Decomposition | Hydrogen cyanide, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen. |
| Fire. | ||||
| Flash Point,°C | 110 | |||
| Autoignition, °C | > 549 | |||
| Fire fighting | Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Contact with water forms corrosive vapors. Contact with water liberates highly flammable gases. Reacts with water, steam or acid to produce toxic and flammable vapors of hydrogen cyanide. Runoff from fire control or dilution water may cause pollution. Extinguishing media: Do NOT get water inside containers. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of water. For small fires, use carbon dioxide, dry chemical, dry sand, or alcohol-resistant foam. Most foams will react with the material and release corrosive/toxic gases. | |||
| Fire potential | Slightly flammable. Toluene diisocyanates will burn but are difficult to ignite. Heat of reaction with aniline may ignite surrounding combustibles and material itself. | |||
| Hazards | When heated to decomposition, it emits toxic fumes of nitrogen oxides. Ventilation should be adequate. If polyurethane products are heated, protection against isocyanate release is necessary. Avoid decomposing heat. | |||
| Combustion products | Toxic oxides of nitrogen are produced during combustion of this material. | |||
| NFPA | Health | 2 | ||
| Flammability | 1 | |||
| Reactivity | 0 | |||
| Health. | |
| Exposure limit(s) | 5 ppb TLV {36 µg/m3} |
| Carcinogin | I-2B, N-2 |
| Poison_Class | 2 |
| Exposure effects | Effects may be delayed. Repeated or prolonged exposure may cause allergic reactions in sensitive individuals. Chronic overexposure to isocyanates has been reported to cause lung damage, including decreased lung fuction, which may be permanent. |
| Ingestion | May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage. May cause cardiac disturbances. May cause central nervous system effects. |
| Inhalation | Causes respiratory tract irritation. May cause liver and kidney damage. Central nervous system effects may include confusion, ataxia, vertigo, tinnitus, weakness, disorientation, lethargy, drowsiness, and finally coma. At high concentrations, isocyanates affect mucous membranes of the respiratory tract and may lead to fatal pulmonary edema. Exposure to low and often even unmeasurable isocyanate concentration results in sensitization. May cause cardiac damage. Can produce delayed pulmonary edema. |
| Skin | Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. Organic isocyanates can cause local irritation and allergic reactions. |
| Eyes | Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury. Lachrymator. May cause chemical conjunctivitis. |
First aid |
|
| Ingestion | Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. |
| Inhalation | Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. |
| Skin | Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. |
| Eyes | Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Do NOT allow victim to rub or keep eyes closed. |
| Transport. | ||
| UN number | 2078 | |
| Response guide | 156 | |
| Hazard class | 6.1 | |
| Packing Group | II | |
| USCG CHRIS Code | TDJ | |
| HS Code | 2929 10 10 | |