n-Amyl methyl ketone
- Methyl amyl ketone
- Heptan-2-one
- 2-Heptanone
n-Amyl methyl ketone | |
| |
| Formula | CH3(CH2)4COCH3 |
| Structure | |
| Description | Water-white liquid with a penetrating fruity odor. |
| Uses | Industrial solvent, solvent for synthetic resin finishes, fragrance ingredient in creams, lotions, perfumes, soaps & detergents, flavor ingredient in foods, inert reaction medium. |
| Registry Numbers and Inventories. | |
| CAS | 110-43-0 |
| EC (EINECS/ELINCS) | 203-767-1 |
| EC Index Number | 606-024-00-3 |
| EC Class | Flammable; Harmful |
| EC Risk Phrase | R 10 20/22 |
| EC Safety Phrase | S 24/25 |
| RTECS | MJ5075000 |
| RTECS class | Primary Irritant |
| UN (DOT) | 1110 |
| Merck | 13,4683 |
| Beilstein/Gmelin | 1699063 |
| Beilstein Reference | 4-01-00-03318 |
| Swiss Giftliste 1 | G-2267 |
| Canada DSL/NDSL | DSL |
| US TSCA | Listed |
| Austrailia AICS | Listed |
| New Zealand | Listed |
| Japan ENCS (MITI) | Listed |
| Korea ECL | Listed |
| Properties. | |
| Formula | C7H14O |
| Formula mass | 114.19 |
| Melting point, °C | -35 |
| Boiling point, °C | 150 |
| Vapor pressure, mmHg | 3 |
| Vapor density (air=1) | 3.9 |
| Saturation Concentration | 2,100 ppm at 25 C; 2,760 ppm at 25 C (calculated) |
| Evaporization number | 17.4 (diethyl ether = 1) |
| Critical temperature | 338 |
| Critical pressure | 29.02 |
| Density | 0.8111 g/cm3 |
| Solubility in water | 0.43 g/100 mL. |
| Viscosity | 0.77 cp (25 C) |
| Surface tension | 26.17 g/s2 |
| Refractive index | 1.40935 (15 C) |
| Partition coefficient, pKow | 1.98 |
| Heat of fusion | 19.7 kJ/mol |
| Heat of vaporization | 46.10 kJ/mol |
| Hazards and Protection. | |
| Storage | Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. |
| WHMIS | B3 D2B |
| Handling | Wash thoroughly after handling. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. |
| Protection | Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. |
| Respirators | Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. |
| Small spills/leaks | Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. |
| Disposal code | 1 |
| Stability | Stable under normal temperatures and pressures. |
| Incompatibilities | Strong oxidizing agents, strong acids, bases. |
| Decomposition | Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. |
| Fire. | ||||
| Flash Point,°C | 49 | |||
| Autoignition, °C | 532 | |||
| Upper exp. limit, % | 5.5 | |||
| Lower exp. limit, % | 1 | |||
| Fire fighting | Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Use agent most appropriate to extinguish fire. Do NOT use straight streams of water. | |||
| Fire potential | Moderate when exposed to heat or flame | |||
| Hazards | Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. | |||
| Combustion products | Irritating vapors and toxic gases, such as carbon dioxide and carbon monoxide, may be formed when involved in fire. | |||
| NFPA | Health | 1 | ||
| Flammability | 2 | |||
| Reactivity | 0 | |||
| Health. | |
| Exposure limit(s) | TLV: 50 ppm; 233 mg/m3 (ACGIH 1995-1996). OSHA PEL: TWA 100 ppm (465 mg/m3) NIOSH REL: TWA 100 ppm (465 mg/m3) NIOSH IDLH: 800 ppm |
| Poison_Class | 4 |
| Exposure effects | Limited studies have generally documented little or no effect of ketones on reproduction in experimental animals. Human data is lacking. 2,5-Hexanedione has an effect on spermatogenesis in male experimental animals. |
| Ingestion | Ingestion of large amounts may cause gastrointestinal irritation. |
| Inhalation | May cause respiratory tract irritation. Vapors may cause dizziness or suffocation. |
| Skin | May cause skin irritation. |
| Eyes | May cause eye irritation. |
First aid |
|
| Ingestion | If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. |
| Inhalation | Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. |
| Skin | Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes. |
| Eyes | Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. |
| Transport. | ||
| UN number | 1110 | |
| Response guide | 127 | |
| Hazard class | 3 | |
| Packing Group | III | |
| USCG CHRIS Code | MAK | |
| USCG Compatatibility Group | 18 Ketones | |
| HS Code | 2914 19 90 | |
| Std. Transport # | 4912032 | |
| IMO Chemical Code | 18 | |
| IMO Pollution Category | D | |